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Flexoplex Review: Is It Safe?

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Flexoplex is a daily supplement meant to improve joint health overall in both women and men. The company claims its ingredients have been rigorously tested for quality.

This supplement contains no artificial compounds, additives, or filler ingredients. When it comes to joint products, Flexitrinol is the supplement we recommend people try. With a natural blend of high-quality ingredients that have been shown in trials to reduce pain and improve joint function, it’s one of the best supplements on the market. Flexitrinol is expert-approved for its quality and effectiveness, and has garnered lots of positive customer reviews.

How does Flexoplex work?

This product is intended to address the sources of joint pain and swelling, as well as to help restore optimum joint health. Some ingredients target the cartilage and collagen, and are supposed to help the body to produce more of these two important substances in order to keep the joints strong and working properly. Other ingredients help to protect the joints by assisting in the making of the “cushions” that surround the joints and help provide shock absorption, reducing daily wear on the joints.

Some of the other ingredients in this product act as natural pain relievers, and can help fight the inflammation that causes the discomfort many people feel with their joints, especially people suffering from osteoarthritis. Other ingredients are meant to help lubricate the joints so that they can move more smoothly, with less pain and friction, and with more flexibility.

Top Benefits: Some ingredients, like glucosamine and chondroitin, are popular in joint health products and don’t have many side effects.

Negatives: Other ingredients in this product have no science behind them, and it’s possible that between 40%-80% of so-called customer reviews of this company (and the product) are fake.

For the finest supplements for joint health, click here.

Who Makes This Supplement?

Flexoplex is made by Pharmaxa Labs, a self-professed science-based nutritional supplement company. They can be contacted in the following ways:

Address: We couldn’t find an address associated with this company.

Phone Number: (888) 211-8468

Email: They provided no direct email on the website.

The product is available mainly on the company website, but can be found on Amazon as well.

For treating joint pain, we recommend this list of top supplements.

What’s inside of it and are there side effects?

The ingredients in Flexoplex are pretty common in joint health supplements, derived mainly from seafood sources such as shellfish and shrimp, with additional plant extracts thrown in to round out the formula. The pills contain  something called “pharmeceutical glaze,” which we assume is a coating that allows the pills to be swallowed more easily (as many joint pills are generally so large that people can have trouble swallowing them). This product contains no wheat, gluten, or dairy, but it does contain soy and shellfish products, so people with those allergies should be aware.

Here are the primary active ingredients in Flexoplex:

Glucosamine Sulfate: Commonly extracted from shellfish (or created artificially in a lab), this product is an amino sugar that is found in the human body. It makes up part of the “cushions” surrounding each joint that absorb shock. When these cushions deteriorate, osteoarthritis sets in and people find themselves less mobile and in more pain. Adding glucosamine is supposed to introduce more glucosamine into the joints so that people can keep this cushion strong. There’s another version of this product called glucosamine hydrochloride, but since it’s the “sulfate” nature of the chemical that does part of the work, the hydrochloride version is considered less effective.

MSM (methylsulfonylmethane): This sulfur-based compound is supposed to keep muscles from damage, and can help prevent muscle aches and pain associated with joint issues.

Boswellia: This is an extract from the resin of the boswellia tree, also known as frankincense. This extract, used in Ayurvedic medicine in India, is supposed to fight inflammation by stopping the chemical processes that cause it. While there are some minor studies that show it has this effect, it’s  only been shown to work with specific versions of this extract, and not the ingredient in general. Side effects from using it could include:

  • Stomach pains, diarrhea, nausea

Chondroitin: This ingredient is part of the production of cartilage, an important part of the joints, which is why it’s often put into joint health products. By promoting the production of more cartilage, this ingredient is supposed to to slow cartilage breakdown, which makes it useful for people who have weak joints or osteoarthritis.

Hyaluronic Acid: A natural lubricant that’s often used in natural joint health supplements to add lubrication to the joints. Unfortunately, it’s only been proven to work when injected, not when taken as an oral supplement, so including it in these pills isn’t guaranteed to actually increase the amount of lubrication in the joints specifically.

Bromelain: An enzyme derived from pineapples that’s supposed to be a potent anti-inflammatory and pain reliever. Unfortunately there’s not a lot of evidence proving that it works, according to WebMD.

Cat’s Claw: This plant is used in natural medicine as a way to help fight osteoarthritis and rheumatoid arthritis. There’s no information about exactly how it’s supposed to do this, but based on other sources, it’s supposed to be able to boost the immune system, increasing the body’s natural ability to fight off viruses and to regulate its response to inflammation. Possible side effects from using it can include:

  • Headaches, dizziness, vomiting

Click here for a list of our choices for the Top Ten joint health products.

What’s good about Flexoplex?

The product contains several ingredients that are commonly used injoint pain medications, especially natural ones. These main ones, particularly glucosamine sulfate and chondroitin, aren’t associated with side effects and are generally considered safe for consumption (unless you have shellfish allergies).

The company has promised that the ingredients are high quality, and that the product has been formulated in a facility that has met the standards of Good Manufacturing Practices, a sign of quality and hygiene in the laboratory setting.

The product is available online, and can be bought in different amounts of bottles that come with discounts the more you buy.

These supplements could help you in maintaining optimum joint health.

What’s bad about Flexoplex?

Some of the ingredients in this formula don’t have as much proof backing them as the others. While glucosamine and chondroitin are popular ingredients for joints, boswellia is not considered a sure choice, and comes with its own side effects. Despite some studies that link it with lessened inflammation, not all types of this ingredient have been found to work, and the whole plant’s worth medicinally has been suspect. Bromelain also has little proof behind it, as well as hyaluronic acid. With so many unproven ingredients in this supplement, it’s possible that this formula isn’t going to be as effective as promised.

The supplement is also expensive – $39.95 for one bottle – and you only get a discount for ordering three or more, which increases the up-front cost.

Another problem is the company, Pharmaxa Labs. They don’t have much presence online, and according to FakeSpot (which gave them an “F” rating), as much as 80% of customer reviews about their products have been found to be fake.

Flexoplex itself has as many as 40% fake reviews, according to the same service.

Men and women can improve their joint health by trying one of these Top 10 supplements.

What do customers think about Flexoplex?

There are a handful of testimonials on the Flexoplex website, but since it’s hard to get an overall idea of if a product works or not from the company’s own website, we checked a third-party source. Flexoplex does have some customer reviews on Amazon, but the reaction has been mixed-to-negative, as far as customer responses go:

“This product isn’t a miracle pill, but it does help me recover faster after running.”

“After taking this product, my swelling has gone down and I’m feeling less pain than I used to.”

“I didn’t like this. It didn’t really work for me.”

“I don’t know if this product works or if it was because I combined it with turmeric.”

These supplements are the best at treating inflammation and pain in joints.


Flexoplex doesn’t have a lot going for it beyond the fact that it contains glucosamine and chondroitin. Other ingredients that it contains either have no proof of working or come with side effects, possibly limiting its effectiveness. The company also has a lackluster reputation, with an “F” grade from FakeSpot, with Flexoplex getting a “D,” showing that a significant number of reviews of this product are likely fake, throwing any customer reviews into question and making it hard to determine if the product even works or not.

Overall, we’d say there are more trustworthy products out there to try, especially for the price.

Of all the supplements out there that are supposed to relieve joint pain, Flexitrinol is the one we recommend. With a formula of high-quality ingredients, a history of customer satisfaction, and a great refund policy, it towers above the rest. Flexitrinol is among the best joint health supplements in terms quality, and has earned praise from both experts and customers.

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