USP Labs Super Cissus RX Review: Is It Safe?

How does USP Labs Super Cissus RX work?

The information on the official website is brief, but they do say that a university review saw that when tested on 29 different athletes, the active ingredient added in the same dosage strength noticed their joint pain went away after 8 weeks of use. The study admitted there were flaws however since there was no:

“placebo-controlled cohort”

It also did not look at effect within:

“women and older adult subjects”

They recommend taking 2 capsules alongside dinner and breakfast and only for people 18 and older. They advise no longer using it if any adverse reactions are experienced.

Other than that there is limited information. They provide a video of athletic looking men working out but they fail to five any actual proof that this works, instead it’s more to show off how they intent for it to be used alongside strenuous activity.

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Top Benefits: The full ingredients are outlined and you know exactly what you’re getting with this product. Direct sales are offered as well.

Negatives: The provided clinical studies are flawed and too limited to consider it a great analysis. Only one key active ingredient is used which has not been proven effective.  The company is facing serious legal charges by the FDA and IRS.

The best joint health supplements were carefully considered after much review.

Who makes this supplement?

USPLabs LLC. Are the owners, here is their contact information:

Address: 10761 King William Dr.

Dallas, TX 75220

Phone Number: (800) 890-3067

Unfortunately they did not post their contact information on their official website, but a phone number is printed on the back of the label. The Better Business Bureau also provided the address.

In 2024 the FDA sent an indictment against the company after they found there were ingredients from China which were falsely labeled. This included a:

“synthetic stimulant”

The reason why this was a major flaw was due to the fact that it may not be safe to use since it is linked to:

“liver toxicity”

Their supplement in question was leading to liver injuries that their customers mentioned. Because pf this the owners of the company may face many years in jail, as well as numerous heavy fines which are yet to be determined. The official charges were conspiracy co commit wire fraud, money laundering, misbranded food, and adulterated food across interstate commerce.

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What’s inside of it and are there side effects?

Here are some of the most notable ingredients:

Cissus Quadrangularis (Stem) Extract: Often used to help support bone and joint health, this is most supplemented by athletes looking to support their bodies after a workout. Some studies have been performed to show what kind of effects is possible. But Examine.com has concluded that:

“More research is needed

They do say that the results are promising, but this does not mean that it is actually guaranteed to work as directed. Examine also conclude with:

“requires a great deal more evidence”

Without more support it’s impossible to know for certain if this would be reliable to use long-term.  Web MD does say that short-term use can potentially cause:

• Diarrhea, headache, and insomnia.
• Gas, dry mouth, and lowered blood sugar.

This is also the only active ingredient inside of this supplement and according to the reviews available online, there has to be more research performed to determine its worth. Even the proper dosage strength is unknown since it may be better absorbed in more or less amounts. It’s unknown why this supplement decided to add this at 1,500 mg per serving.

Corn Starch: A basic starch taken from the corn kernel. This is added as a filler ingredient to help fill up the capsules in this supplement. Because corn is typically well-tolerated, it’s unlikely to cause any side effects. Typically filler ingredients like this are only used to make the capsules appear to be much fuller than they actually are, it’s very cheap to source and makes for an easy to add ingredient.

Silicon Dioxide: Common filler ingredient which can come from many different minerals such as quartz.  When breathed in it may be a potential allergen and toxic ingredient that can lead to bronchitis and other lung related issues. This is typically considered non-toxic when taken in small amounts added to supplements.

Titanium Dioxide Color: A natural mineral that can thicken and provide color. This is often added to sunscreen and it is used because of the belief it is less irritable than similar ingredients.

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What’s good about USP Labs Super Cissus RX?

You know exactly what you’re getting with this since they highlight the full supplements facts list with a magnifying web application where you can read the contents. They also provide a full 5 week supply and offer direct sales of this supplement.

It is also good that they actually had studies performed on it since it shows that spent time to try and show its value.

Each bottle lasts a grand total of 5 weeks which is often more than the average supplement.

What’s bad about USP Labs Super Cissus RX?

Their study was flawed since it only was tested on young athletic men, and no women or older adults used it. This study failed to compare it to a placebo so it could be that because the test group taking it knew it was for joint health, they may have had a placebo effect. Only 29 people used it which is a very small sample size to compare results to.

All that’s provided is just one active ingredient that although is added in a high dosage strength, isn’t as well-rounded as other joint health supplements.

In looking at the research though the sole active ingredient is seen as promising, there still has to be more research to determine if it’s truly effective. Without more data it’s impossible to tell if it will have lasting results.

The pending lawsuit alleges that the company introduced potentially dangerous ingredients into their supplements which were shown to cause liver damage to consumers.

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What do consumers think about USP Labs Super Cissus RX?

“great way to treat both pain and inflammation, been working as directed”

“I am a professional athlete and have not noticed an improvement in any way in my joints”

“Not sure if this is as good as it’s claimed but so far so good for my needs”

“Helped get rid of pain but not during a workout so I don’t think it’s that great. More for soreness than anything else if that’s what you want”

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